abstract：:Phosphatidylcholine (PC) metabolism in bovine adrenal chromaffin cells has been studied in vivo with 100 MHz 13C NMR spectroscopy. The incorporation of 13[CH3]choline was examined in cells embedded in 1% agarose strands and perfused at 37 degrees C. The pattern of 13C NMR spectroscopy. The incorporation of [13CH3]chol...

journal_title：NMR in biomedicine

authors： Rivera CJ,Plishker GA,Morrisett JD,Moore J,Percy AK

更新日期：1991-06-01 00:00:00

abstract：:1H NMR spin-echo spectroscopy has been used to study the metabolism of exogenous compounds in human erythrocytes. The non-invasive nature of the technique and the continuous monitoring makes it ideal to investigate both the conversion of substrates and the occurrence and the nature of the products. Hydrolysis rates ma...

journal_title：NMR in biomedicine

authors： Skibsted U,Hansen PE

更新日期：1990-12-01 00:00:00

abstract：:Normal subjects performed voluntary, isometric exercise 1 s contraction, 1 s rest for 10 min) of the first dorsal interosseous (FDI) muscle with a target force of 25, 50 and 100% of the maximal voluntary contraction (MVC) force. 31P NMR spectra were collected continuously before, during and after exercise. Data were a...

journal_title：NMR in biomedicine

authors： Newham DJ,Cady EB

更新日期：1990-10-01 00:00:00

abstract：:Blood flow and phosphorus metabolites have been measured simultaneously in the murine RIF-1 tumour in vivo. Blood flow was measured using the H2 washout technique and 31P NMR spectroscopy was used to measure high energy phosphates, inorganic phosphate and intracellular pH within the tumour. Following NMR and flow meas...

journal_title：NMR in biomedicine

authors： Bhujwalla ZM,Tozer GM,Field SB,Proctor E,Busza A,Williams SR

更新日期：1990-08-01 00:00:00

abstract：:Spin-exchange NMR techniques enable the measurement of the rates of exchange of solutes between chemically or physically distinct sites in reactions taking place at chemical equilibrium. The time scale of the events that are able to be investigated lies in the neighbourhood of 1 s. The earliest studies in this area of...

journal_title：NMR in biomedicine

authors： Kuchel PW

更新日期：1990-06-01 00:00:00

abstract：:31P Nuclear magnetic resonance spectroscopy has been used to investigate the combined effect of 70 mM ethanol administration and hypoxia on the energetic metabolism and cytosolic pH of the perfused liver isolated from naive, fasted or chronically ethanol-treated rats. Ethanol-treatment or fasting induce a similar 25% ...

journal_title：NMR in biomedicine

authors： Desmoulin F,Canioni P,Masson S,Gérolami A,Cozzone PJ

更新日期：1990-06-01 00:00:00

abstract：:A simple technique permitting long term 31P magnetic resonance spectroscopy of cultured mammalian cells is described. Cells are encapsulated in calcium alginate gels and perfused with a new phosphate-fre medium designed for maintenance of high cell viability. Intracellular pH and beta-NTP/Pi ratios, studied in three c...

journal_title：NMR in biomedicine

authors： Narayan KS,Moress EA,Chatham JC,Barker PB

更新日期：1990-02-01 00:00:00

abstract：:The potential use of 13C multilabeled substrates has been studied in biological applications using in vivo and in vitro proton and 13C NMR spectroscopy. In 13C NMR spectroscopy, multilabeled compounds allow the simultaneous observation of several nuclei or increase distinctly the signal to noise ratio due to a higher ...

journal_title：NMR in biomedicine

authors： Künnecke B,Cerdan S

更新日期：1989-12-01 00:00:00

abstract：:Localization techniques are considered an indispensable part of the clinical spectroscopy examination. The results are often a marked improvement in diagnostic information (amplification), but because of the introduction of new artifacts and the more prolonged examination time, some of the undoubted advantage is lost ...

journal_title：NMR in biomedicine

authors： Ross B,Narasimhan PT,Tropp J,Derby KS

更新日期：1989-12-01 00:00:00

abstract：:Progress in the development of non-proton NMR applications in medical research has been hampered by the generally low sensitivity of these nuclides as well as the lack of instrumentation readily available for studying these spins. For example, custom head coils suitable for sodium imaging of the human head are either ...

journal_title：NMR in biomedicine

authors： Lim KO,Wolff S,Balaban RS

更新日期：1989-09-01 00:00:00

abstract：:The myeloproliferative leukemic virus (MPLV) induces within 2-3 weeks a massive infiltration of the adult mouse liver by hematopoietic leukemic cells. Since the metabolism of the infiltrated organ might be correlated with an interaction of two cell populations, it was decided to study the isolated hematopoietic cells ...

journal_title：NMR in biomedicine

authors： Mégnin F,Nedelec JF,Dimicoli JL,Lhoste JM

更新日期：1989-06-01 00:00:00

abstract：:This review assesses the progress of NMR in the field of hemorheology, i.e., the assessment of the mechanical and physical characteristics of flowing blood. The review deals with the intrinsic rheological properties of the red cell and its constituents (membrane, cytoplasm), which are dominant in the microcirculation,...

journal_title：NMR in biomedicine

authors： Berling C,Hall LD

更新日期：1989-06-01 00:00:00

abstract：:An evaluation of the reproducibility and accuracy of the NMR human blood test for cancer described by Fossel, E. T., Carr, J. M. and McDonagh, J., (New England Journal of Medicine 315, 1369-1376) in 1986 has been conducted jointly at the National Cancer Institute-Frederick Cancer Research Facility, Frederick, MD (NCI-...

journal_title：NMR in biomedicine

authors： Chmurny GN,Hilton BD,Halverson D,McGregor GN,Klose J,Issaq HJ,Muschik GM,Urba WJ,Mellini ML,Costello R

更新日期：1988-06-01 00:00:00

abstract：:The phosphorus NMR spectra of isolated perfused rat liver displays a prominent inorganic phosphate peak at 2.76 +/- 0.05 ppm relative to liver glycerolphosphocholine at 0.49 ppm. From titration curves of phosphorus-containing compounds this corresponds to a pH of 7.4. The spectra also display a shoulder on the promine...

journal_title：NMR in biomedicine

authors： Thoma WJ,Uğurbil K

更新日期：1988-04-01 00:00:00

abstract：:Surface coil 13C nuclear magnetic resonance (NMR) spectroscopy was used to investigate the in vivo carbohydrate metabolism of rat C6 gliomas during and after infusion with [1-13C] glucose. In vivo 1H-decoupled 13C NMR spectra of the glioma following infusion with [1-13C]glucose revealed the direct production of [3-13C...

journal_title：NMR in biomedicine

authors： Ross BD,Higgins RJ,Boggan JE,Willis JA,Knittel B,Unger SW

更新日期：1988-02-01 00:00:00